Senior Research Nurse (Fixed Term) – TITAN-TBI Trial

About the role

The University of Cambridge's Department of Clinical Neurosciences is seeking a Senior Research Nurse for a fixed-term (3 years) post in the TITAN-TBI clinical trial team. The trial tests whether Tocilizumab, an anti-IL-6r monoclonal antibody, reduces neuroinflammation and secondary brain injury after severe head injury. The post-holder manages the day-to-day running of the trial, including recruitment, biosample collection and processing, and runs brain injury biomarker and immunology assays. The appointment is an integrated one between the University and Cambridge University Hospitals NHS Foundation Trust, with an Honorary Research Contract issued by the NHS Trust.

Key responsibilities

• Deliver high-quality, patient-focused clinical research in line with GCP, the NHS Research Governance Framework, clinical trials legislation and local SOPs
• Recruit eligible participants, obtain informed consent and act as a key contact for participants and their families
• Collect and process biosamples (blood, cerebral microdialysate, cerebrospinal fluid) and run simple laboratory assays under the supervision of an experienced laboratory manager
• Collect and record clinical data, report adverse events and protocol deviations, and deliver neuropsychometric assessments
• Work with multidisciplinary teams and liaise with R&D, pharmacy, finance, imaging and laboratories

Required profile

• NMC-registered Nursing Practitioner permitted to practise in the UK
• Relevant clinical experience at the level of NHS Band 5 or above, in neurocritical care, including familiarity with cerebral microdialysis catheters
• Experience in clinical research environments such as clinical trials and participant recruitment
• Ability to communicate sensitively with families of critically ill patients

Required skills

• Current GCP certificate and knowledge of UK clinical research infrastructure and regulations
• Numeracy, good IT skills and competence in Windows, Microsoft Excel and Microsoft Access
• Ability to perform neuropsychometric assessments
• Experience coordinating submissions to REC, HRA, MHRA and local R&D

Applicants must apply online through the University's recruitment system, uploading a covering letter, CV and the Additional Information for Clinical Researchers form, and state their referees. The closing date is 22 November 2026; the salary is £43,099-£49,798. The University has a hybrid working policy.