Medical Director - Oncology Clinical Development (GI)

About the role

GSK is looking for a Medical Director for Oncology Clinical Development in gastrointestinal (GI) oncology. The role sits within the clinical programme team, acting as the physician responsible for medical monitoring, safety oversight and the interpretation of clinical and safety data. It works within the strategy set by the Clinical Development Lead and is a core member of the Clinical Matrix Team. Candidates who want to be based in Stevenage will be temporarily based there, with the office planned to move to Cambridge by early 2029.

Key responsibilities

• Lead medical monitoring and safety oversight of clinical studies, including eligibility decisions, protocol queries, safety data review and participation in SRT and IDMC meetings
• Contribute to protocol development, the informed consent form, the protocol deviation management plan and the study reference manual
• Interpret clinical and safety data and help shape study-level and programme-level decisions
• Help write scientific communications, including study reports, publications and congress materials, and work with investigators on abstracts and manuscripts
• Contribute to regulatory documents, Health Authority interactions and regulatory submissions, and engage with Key External Experts and investigators
• Represent the medical view in cross-functional discussions with Clinical Operations, Biostatistics, Regulatory and Pharmacovigilance, and in the Clinical Matrix Team

Required profile

• MD (or equivalent medical degree) with board certification or eligibility in oncology, haematology or a related specialty
• Clinical experience in oncology or related areas, with exposure to clinical research or drug development
• Experience in clinical trial conduct, including medical monitoring, safety review and data interpretation
• Experience in cross-functional matrix teams in a pharma, biotech or academic clinical trial setting

Required skills

• Knowledge of GCP, ICH guidelines and global regulatory frameworks
• Ability to apply clinical judgement to study design, patient safety and real-time medical decisions
• Scientific communication skills
• Preferred: GI oncology Phase I-III experience, regulatory interaction experience, KEE engagement, and familiarity with real-world evidence and AI-enabled insights

The role requires an on-site office presence 2 to 3 days a week in the UK, Switzerland or the US. Applicants submit a CV and a short cover letter explaining their fit for the role.