Senior Medical Director, Oncology Clinical Development - Sarcoma

About the role

GSK is recruiting a Senior Medical Director for Oncology Clinical Development in Sarcoma, a senior physician leader who provides medical oversight, strategic clinical insight and a patient-centred perspective across the design, conduct and interpretation of clinical studies. The role sits within the clinical strategy defined by the Clinical Development Lead, works closely with the Senior Scientist and cross-functional teams, and is a senior member of the Clinical Matrix Team. It requires an on-site office presence of at least two days per week at one of GSK's Switzerland, UK or US sites.

Key responsibilities

• Provide medical oversight and guidance on medical monitoring and safety oversight across studies, ensuring consistent clinical judgement and patient safety
• Interpret complex clinical and safety data and contribute to programme-level benefit-risk assessments and clinical positioning
• Give senior medical input into protocol development and study design, and resolve complex medical questions during study conduct
• Engage with investigators, Key External Experts and scientific leaders, representing the programme at advisory boards, steering committees and scientific forums
• Mentor Medical Directors and clinical scientists within the programme
• Contribute to regulatory interactions, external scientific engagement and clinical and technical diligence of business development opportunities
• Serve as a senior member of the Clinical Matrix Team and lead or contribute to Oncology Clinical Development-wide initiatives

Required profile

• Medical degree with advanced specialty training, fellowship or equivalent in medical oncology, paediatric oncology or haematology
• Experience in sarcoma oncology, including leading drug development
• Experience in medical monitoring, safety evaluation and clinical data interpretation
• Understanding of clinical development, GCP, ICH guidelines and global regulatory frameworks
• Experience in cross-functional matrix teams
• Preferred: deep expertise in soft tissue sarcoma and osteosarcoma, Phase I-III experience, regulatory interaction experience (IND, scientific advice, NDA/MAA), KEE engagement, publications and diligence experience

What we offer

• For candidates based in Cambridge, MA; Waltham, MA; Rockville, MD or San Francisco, CA, the annual base salary for new hires ranges from $284,250 to $473,750
• An annual bonus and eligibility for a share-based long-term incentive programme depending on role level
• Healthcare and other insurance benefits for employee and family, retirement benefits, paid holidays, vacation and paid caregiver/parental and medical leave