Protein Scientist

About the role

Are you an experienced Protein Scientist looking to make an impact in drug discovery? Join a leading pharmaceutical company's Molecular Sciences team to develop recombinant protein expression and purification strategies that support structural biology, biophysics and early‑stage drug discovery programmes.

Key responsibilities

• Develop recombinant protein expression in prokaryotic and eukaryotic systems.
• Optimise protein purification using AKTA chromatography.
• Produce high‑quality proteins for structural biology and biophysical studies.
• Support multidisciplinary drug discovery projects.
• Collaborate with internal scientists and external partners.

Required profile

• PhD with relevant post‑doctoral or industry experience.
• Strong background in recombinant protein expression and purification.
• Experience with chromatographic techniques and protein characterisation (e.g., AKTA).
• Experience with membrane proteins or multi‑subunit protein complexes (essential).
• Excellent communication and teamwork skills.

Required skills

• Recombinant protein expression
• Protein purification
• AKTA chromatography
• Protein characterisation
• Membrane proteins
• Multi‑subunit protein complexes
• Cryo‑EM
• X‑ray crystallography
• NMR
• SPR
• ITC
• Mass spectrometry
• TSA/DSF
• Nanodiscs
• AI/ML for construct design
• Fragment‑based drug discovery (FBDD)
• Structure‑based drug discovery (SBDD)

What we offer

• 2‑year fixed‑term contract.