Senior Medical Director, Ophthalmology Precision Medicine

About the role

Within Roche's Pharma Research & Early Development (pRED), the Ophthalmology teams are building a new Ophthalmology Precision Medicine function from the ground up at the Welwyn site. The role defines the vision, structure and scientific direction of a group combining biomarker science, advanced imaging, clinical expertise and artificial intelligence, and leads a cross-functional team across translational medicine, imaging, clinical development, data science and biomarkers.

Key responsibilities

• Define the vision, structure and scientific direction of the new precision medicine group.
• Lead a cross-functional team and bridge laboratory science and clinical practice through fluid- and imaging biomarker strategies.
• Direct ophthalmic imaging approaches including OCT, OCT-A and FA to inform clinical practice and therapeutic development.
• Integrate preclinical and clinical datasets using classical and next-generation analytical approaches.
• Influence portfolio strategy across neovascular AMD, diabetic macular edema, geographic atrophy and intermediate AMD.
• Represent Roche externally with scientific experts, investigators and the ophthalmology community.

Required profile

• Board-certified ophthalmologist (MD or MD/PhD) with expertise in ophthalmology, translational medicine or biomedical sciences.
• Recognised expert in the retina space with a strong publication record and key opinion leader status.
• Deep knowledge of ophthalmic imaging technologies and experience with imaging analysis or Reading Centre environments.
• Experience integrating preclinical and clinical data for proof of biology, efficacy and safety, with some exposure to clinical trials.
• Collaborative scientific leader comfortable in matrix environments.

Preferred

• Experience applying AI or machine learning to ophthalmic imaging analysis or clinical data.
• Prior experience in pharmaceutical drug development programmes for retinal diseases.
• Flexible working arrangements may be available for exceptional candidates who want to keep some clinical activity.